(1) Other normal inhabitants of the birth canal - staph, strep, diphtheroids, anaerobes , E. coli and Listeria - are other pathogens that may cause neonatal pneumonia.(2) Major and limb-threatening infections usually are polymicrobial and may involve aerobic gram positive cocci, gram negative bacilli, anaerobes , and enterococci.(3) Foot infections in diabetic patients are commonly polymicrobial and may involve aerobes and anaerobes .(4) The most recently released agents have significant antimicrobial activity against gram-positive streptococci, atypical pathogens and anaerobes .(5) Organisms that preferentially attack the fallopian tubes include Neisseria gonorrhoeae, Chlamydia trachomatis and mixed aerobes and anaerobes .