(1) Gating currents represent intramolecular motions of ion channels in response to changes in transmembrane potential.(2) This tertiary structure is stabilized by salt bridges, intramolecular hydrogen bonds, and four disulfide bridges.(3) Studies of protein dynamics have shown that the interaction of the protein surface with the water molecule strongly increases the intramolecular mobility of the protein.(4) The attractions of molecules for each other are called intermolecular interactions to distinguish them from covalent and ionic bonding, forms of intramolecular interactions.(5) Here we seek to study inter- and intramolecular forces among water and biological molecules as models of the rudimentary interactions that govern protein folding.(6) The PCR-generated constructs were ligated intramolecularly .(7) Experimental AFM observations of intramolecularly condensed polyelectrolytes confirm the above predictions.(8) These belong to the network of strongly intramolecularly interacting residues, that become buried upon dimer formation, and interact intermolecularly with the same network of the other monomer.(9) There are several characteristic morphologies for intramolecularly condensed polyelectrolytes.(10) By binding intramolecularly to the receptor, the tethered ligand causes transmembrane signaling.
