
The answer is MINUS eight pi alpha.
The Big Bang Theory Season 1, Episode 13

Do you know how to integrate X squared
times E to the MINUS X without looking it up?
The Big Bang Theory Season 8, Episode 2

A hydrogen atom, H,
plus pigs MINUS P, "higs."
The Big Bang Theory Season 3, Episode 13

MINUS cash on hand...
Breaking Bad Season 2, Episode 3

Yeah, MINUS five,
The Big Bang Theory Season 11, Episode 12